Effect of compund antioxidant medication (Sperigen tablet) on sperm DNA Fragmentation Index in infertile men aged 20 to 40 years
Phase 1
Recruiting
- Conditions
- male infertility.
- Registration Number
- IRCT20230831059309N1
- Lead Sponsor
- Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 60
Inclusion Criteria
Infertile men with abnormal spermogram (Idiopathic)
age range 20 to 40 years
absence of hormonal, anatomical and congenital anomalies of the urogenital system,
lack of antioxidant medication usage or drugs affecting spermogram parameters such as nitrofurantoin, corticosteroids and antineoplastic.
Exclusion Criteria
Men with normal spermogram
use of drugs, cigarrette and waterpipe smoking
patients outside the specified age range
varicocele
patients with Diabete, thyroid problem or any other internal disease affectting spermogram
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of sperm DFI , total sperm count and total motile sperm in semen analysis. Timepoint: Measurement of DNA fragmentation Index before starting and 3 months after taking the drug. Method of measurement: Sperm Chromatin Structure Assay lab test (SCSA).
- Secondary Outcome Measures
Name Time Method