comparing the effect of two drugs (Dexmedetomidine and lignocaine) in reducing the rise in heart rate, blood pressure during recovery from anaesthesia
Phase 2/3
Recruiting
- Conditions
- Age group between 18 and 65years of eithergender belonging to ASAPS 1 or 2 undergoingLaproscopic surgery
- Registration Number
- CTRI/2018/03/012555
- Lead Sponsor
- PG Thesis fund KMC Manipal
- Brief Summary
The study is Prospective Double blinded Randomized Controlled study. Main aim is to compare the efficacy of intravenous Dexmedetomidine and Lignocaine in attenuating haemodynamic responses to tracheal extubtion and emergence from general anaesthesia. primary outcomes are Heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure during periextubation period. secondary outcomes is to observe sedation score and time to extubation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
to ASA-PS I and II undergoing elective laproscopic surgeries requiring general anaesthesia and endotracheal intubation.
Exclusion Criteria
Suspected allergy to study drugs, Difficult airway,.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To observe and compare heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure in the periextubation period Heart rate, Systolic, diastolic and mean arterial pressures at intervals | Baseline(just before drug administration) | After 5 min (end of drug administration) | Post extubation at 1, 2, 3, 4, 5 and 10 min.
- Secondary Outcome Measures
Name Time Method Ramsay sedation score Time to extubaton
Trial Locations
- Locations (1)
Kasturba Medical College and Hospital
🇮🇳Udupi, KARNATAKA, India
Kasturba Medical College and Hospital🇮🇳Udupi, KARNATAKA, IndiaDr Chiranjeevi vallamsettyPrincipal investigator9845544346drchiru2k7@gmail.com