Skip to main content
MedPathMedPath Home
Clinical Trials/NCT02742298
NCT02742298
Completed
Not Applicable

Electrical Impedance Myography and Muscle Ultrasound: Longitudinal Measures in Pompe Disease

Duke University1 site in 1 country25 target enrollmentOctober 24, 2016
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsPompe Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pompe Disease
Sponsor
Duke University
Enrollment
25
Locations
1
Primary Endpoint
Percent change in muscle ultrasound echointensity as compared to baseline
Status
Completed
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Study Objectives:

  1. Determine the correlation between quantitative muscle ultrasound (QMUS), electrical impedance myography (EIM) and currently accepted measures of physical function.
  2. Determine the reliability of EIM measures performed in the home through use of a hand held device.
  3. Determine if QMUS and EIM can detect pre-clinical changes in Pompe disease.
Registry
clinicaltrials.gov
Start Date
October 24, 2016
End Date
July 31, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Genetically confirmed diagnosis of Pompe disease.

Exclusion Criteria

  • •Age \<18 years
  • •Inability to provide informed consent.

Outcomes

Primary Outcomes

Percent change in muscle ultrasound echointensity as compared to baseline

Time Frame: Baseline, 1-2 years

Percent change in muscle electrical impedance myography as compared to baseline

Time Frame: Baseline, 1-2 years

Secondary Outcomes

  • Inter-rater reliability of muscle ultrasound and electrical impedance myography measures(1-2 years)

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Establishing Muscle Impedance Parameters With Electrical Impedance MyographyIBMInclusion Body Myositis
NCT03633318Yale University31
Active, not recruiting
Not Applicable
Ultrasonographic Muscle Assessment and Functional Scales in Spinal Muscular AtrophySpinal Muscular Atrophy (SMA)Neuromuscular Disease
NCT06599606Istanbul University - Cerrahpasa (IUC)34
Completed
Not Applicable
Relation Between Bioelectrical Impedance Analysis (BIA) and CT-scan Analysis in the ICUMuscular Atrophy
NCT02555670Amsterdam UMC, location VUmc222
Completed
Not Applicable
Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower LimbStrokeSpasticity, Muscle
NCT06411587Universidad de Zaragoza52
Completed
Not Applicable
Ultrasound Imaging of Quadriceps Muscle in Patients With Knee OsteoarthritisOsteoarthritis, Knee
NCT04660071Hacettepe University30