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Clinical Trials/NCT04017182
NCT04017182
Unknown
Not Applicable

Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

Ramathibodi Hospital1 site in 1 country40 target enrollmentApril 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Central Venous Oxygen Saturation
Sponsor
Ramathibodi Hospital
Enrollment
40
Locations
1
Primary Endpoint
Correlation of venous oxygen saturation
Last Updated
5 years ago

Overview

Brief Summary

After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory for venous blood gas analysis. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.

Detailed Description

All patients age between 18-65 year old who undergoing surgery under general anesthesia and superior vena cava central venous catheter installation anticipated are eligible. The tips of superior vena cava central venous catheter was confirmed by Chest x-ray. Next 1 hour after skin incision, 1 ml of venous blood sample is taken from superior vena cava central venous catheter of right external jugular vein then send to central laboratory for venous blood gas analysis. The demographic data will be recorded. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined the primary outcome and partial pressure of carbon dioxide will be determined as a secondary outcome.

Registry
clinicaltrials.gov
Start Date
April 1, 2021
End Date
December 1, 2021
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Thanist Pravitharangul

Principal investigator

Ramathibodi Hospital

Eligibility Criteria

Inclusion Criteria

  • Written consent obtained from patient or next of kin a day before operation date
  • Patient age between 18-65 years old undergoing syrgery under general anesthesia
  • Superior vena cava central venous catheter anticipated for CVP mesurement, innotropic or vasopressor administration,pulmonary artery catheter insertion route
  • Anticipated right external jugular venous sampling time less than 5 minutes
  • The site of blood sample collection easily access during operation

Exclusion Criteria

  • No jugular central venous catheter installation or other route selected
  • Duration of paired sample collection more than 10 minutes
  • Can not collected blood sample from right external jugular vein within 3 attemps
  • The site of blood sample collection difficulty access during operation
  • Pateint or next of kin refuse to participate

Outcomes

Primary Outcomes

Correlation of venous oxygen saturation

Time Frame: 1 hour

Correlation of venous oxygen saturation between external jugular vein and superior vena cava

Secondary Outcomes

  • Correlation of venous partial pressure of carbon dioxide(1 hour)
  • Relationship between superior vena cava central venous and external jugular venous oxygen saturation(1 hour)

Study Sites (1)

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