Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Ramathibodi Hospital
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Correlation of venous oxygen saturation
Study Overview
Brief Summary
After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory for venous blood gas analysis. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.
Detailed Description
All patients age between 18-65 year old who undergoing surgery under general anesthesia and superior vena cava central venous catheter installation anticipated are eligible. The tips of superior vena cava central venous catheter was confirmed by Chest x-ray. Next 1 hour after skin incision, 1 ml of venous blood sample is taken from superior vena cava central venous catheter of right external jugular vein then send to central laboratory for venous blood gas analysis. The demographic data will be recorded. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined the primary outcome and partial pressure of carbon dioxide will be determined as a secondary outcome.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Written consent obtained from patient or next of kin a day before operation date
- •Patient age between 18-65 years old undergoing syrgery under general anesthesia
- •Superior vena cava central venous catheter anticipated for CVP mesurement, innotropic or vasopressor administration,pulmonary artery catheter insertion route
- •Anticipated right external jugular venous sampling time less than 5 minutes
- •The site of blood sample collection easily access during operation
Exclusion Criteria
- •No jugular central venous catheter installation or other route selected
- •Duration of paired sample collection more than 10 minutes
- •Can not collected blood sample from right external jugular vein within 3 attemps
- •The site of blood sample collection difficulty access during operation
- •Pateint or next of kin refuse to participate
Outcomes
Primary Outcomes
Correlation of venous oxygen saturation
Time Frame: 1 hour
Correlation of venous oxygen saturation between external jugular vein and superior vena cava
Secondary Outcomes
- Correlation of venous partial pressure of carbon dioxide(1 hour)
- Relationship between superior vena cava central venous and external jugular venous oxygen saturation(1 hour)
Investigators
Thanist Pravitharangul
Principal investigator
Ramathibodi Hospital