Predictors of Successful Extubation of Pediatric Patients From Mechanical Ventilation With or Without Post Extubation High Velocity Nasal Insufflation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- comparing the need for reintubation within 48 hours afterr extubation using High Velocity Nasal Insufflation versus simple oxygen
研究概览
简要总结
A randomized clinical trial about predictors of successful extubation of pediatric patients from mechanical ventilation either on High Velocity Nasal Insufflation or simple nasal oxygen and comparing the outcome
详细描述
A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or reintubation within 48 hours, presence of respiratory distress or stridor post extubation, knowing mechanical ventilaton free days after extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 2 Months 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 2 months and 13 years old with minimum weight 4kg
- •Both sexes
- •Patients on mechanical ventilation for at least 24 hours for any indication
排除标准
- •Patients not ready for weaning from mechanical ventilation
- •Contraindications to use of High velocity nasal insufflation
- •Prolonged mechanical ventilation for more than 21 days
研究组 & 干预措施
Exubation of pediatric patients on High Velocity Nasal Insufflation
干预措施: Comparing the outcome of pediatric patients after successful weaning on either High Velocity Nasal Insufflation or simple oxygen (Device)
Exubation of pediatric patients on High Velocity Nasal Insufflation
干预措施: comparing High Velocity Nasal Insufflation to simple oxygen after successful weaning of pediatric patients (Device)
Exubation of pediatric patients on simple oxygen
干预措施: Comparing the outcome of pediatric patients after successful weaning on either High Velocity Nasal Insufflation or simple oxygen (Device)
Exubation of pediatric patients on simple oxygen
干预措施: comparing High Velocity Nasal Insufflation to simple oxygen after successful weaning of pediatric patients (Device)
结局指标
主要结局
comparing the need for reintubation within 48 hours afterr extubation using High Velocity Nasal Insufflation versus simple oxygen
时间窗: 48 hours
Successful extubation with no need for reintubation within 48 hours among pediatric ICU patients in those using High Velocity Nasal Insufflation versus simple oxygen
次要结局
未报告次要终点
研究者
Sherin Tarek Fayez Ali
Cairo University
Cairo University