The Behavioral and Neural Effects of Oxytocin on Face Perception in Congenital Prosopagnosia
试验速览
- 阶段
- 早期 1 期
- 状态
- 暂停
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Memory performance
研究概览
简要总结
The purpose of this study is to determine whether oxytocin affect face perception
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •normal or corrected to normal vision
排除标准
- •pregnancy (according to a pregnancy test taken by subjects prior to participation)
- •a history of asthma or nasal polyps
- •cardiac disorders
- •hyponatremia
- •acute or chronic renal insufficiency
- •liver cirrhosis
- •neurological disease
- •other chronic disease
- •dementia, or lack of judgment
研究组 & 干预措施
Control group
Control group will be administered oxytocin and placebo, in a double-blind randomized order.
干预措施: Oxytocin (Drug)
Control group
Control group will be administered oxytocin and placebo, in a double-blind randomized order.
干预措施: Placebo (Drug)
congenital prosopagnosia
Congenital prosopagnosics will be administered oxytocin and placebo in a double-blind randomized order.
干预措施: Oxytocin (Drug)
congenital prosopagnosia
Congenital prosopagnosics will be administered oxytocin and placebo in a double-blind randomized order.
干预措施: Placebo (Drug)
结局指标
主要结局
Memory performance
时间窗: Day 2 (24 hours after encoding)
At the day participants will administer the substance, they will view a set of faces, of which they will be tested about 24 hours later. The measures that will be tested are %accuracy and %dwell time of eye movements towards each region in the faces the participants saw.
次要结局
- Mood measurement(Day 1 (after oxytocin/placebo uptake))
研究者
Ilan Shelef
Head of medical imaging at Soroka University Medical Center
Soroka University Medical Center