Neuromuscular Block Monitoring During Monitored Thyroidectomy

Completed

• Conditions: Thyroid Surgery

• Registration Number: NCT04982185
• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital

Brief Summary

Titration of neuromuscular block (NMB) plays a key role in intraoperative recurrent laryngeal nerve monitoring during thyroid surgery. Aim to titrate sugammadex dose based on neuromuscular block degree as a surgeon friendly protocol with high intraoperative neuromonitoring (IONM) quality.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-01
• Primary Completion: 2020-07-31
• Study First Submitted: 2021-06-20
• Study First Submitted QC: 2021-07-22
• Study First Posted: 2021-07-29
• Study Completion: 2021-07-31
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-07
• Last Update Posted: 2021-10-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• elective monitored thyroidectomy

Exclusion Criteria

• previous thyroid surgery
• preexisting vocal cord palsy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility in neural monitoring	through surgery completion, an average of 2 hours	EMG amplitude

Secondary Outcome Measures

Name	Time	Method
Quality of surgical relaxation	through surgery completion, an average of 2 hours	patient movement assessed as severe, mild or none by a departmental scale (none=no movement, mild: any movement did not interfere operation, severe: any movement interrupt operation)

Trial Locations

Locations (1)

I-Cheng Lu; 🇨🇳 Kaohsiung, Select, Taiwan