Renal Function During Laparoscopic Surgery

Not Applicable

Completed

• Conditions: Intra Operative Fluid Management
• Interventions: Drug: Dopamine

• Registration Number: NCT01722630
• Lead Sponsor: Catholic University of the Sacred Heart

Brief Summary

Aim of this study was to investigate the cardiac and renal responses to the administration of different amount of crystalloids, with and without dopamine, during gynaecological laparoscopic surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Primary Completion: 2012-07
• Study Completion: 2012-10
• Status Verified: 2012-11
• Study First Submitted: 2012-11-02
• Study First Submitted QC: 2012-11-05
• Last Update Submitted: 2012-11-05
• Study First Posted: 2012-11-07
• Last Update Posted: 2012-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• ASA I
• age 24-42
• patients undergoing gynaecological laparoscopy

Exclusion Criteria

• cardiovascular diseases
• renal and endocrine disorders
• obesity (BMI > 30 Kg/m2)
• the assumption of drugs that could interfere with renal parameters considered in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
dopamine	Dopamine	Patients received intravenously saline solution at 5 ml/Kg/h and dopamine at 3 mcg/Kg/min

Primary Outcome Measures

Name	Time	Method
estimated glomerular filtration rate, tissue Doppler imaging, E/Ea	patients will be followed for the duration of surgery, an expected average of 3 hours	EGFr, tissue Doppler imaging and E/Ea are registered after the induction of pneumoperitoneum and Trendelemburg position, and compared to those registered before the induction of anesthesia.

Secondary Outcome Measures

Name	Time	Method
total intra operative diuresis (TID)	patients will be followed for the duration of surgery, an expected average of 3 hours	TID will be measured at the end of surgery

Trial Locations

Locations (1)

Catholic University of the sacred Heart; 🇮🇹 Rome, Italy