Effect of dopamine on renal function in diabetic patients undergoing cardiac surgery

Phase 2

• Conditions: Diabets type I,II.; Diabetes mellitus; (E10-E14)

• Registration Number: IRCT2015110823716N1
• Lead Sponsor: Vice Chancellor for Research, Shiraz University of Medical Sc

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

CABG surgery patients with heart bypass; diabetic patients; patients with EF more than 30%
Patients with BUN lower than 30 mg / dl; Patients with serum creatinine less than 5 mg / dl1.5

Exclusion criteria: Age over 70 years; The combined surgical procedure; reoperation; The use of balloon pump; hyper-thyroidism; patients with contraindications for use dopamine such as pheochromocytoma; dialysis for history of Renal Failure; patients with serum creatinine equal to or more than 1.5 dl / mg; patients with EF equal and less than 30%, patients with BUN more than 30 dl / mg; patients with kidney and liver problems; patients who we had to use a higher dose of 0.05 isotropic in the operating room and ICU; The left ventricular dysfunction

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Renal function. Timepoint: At 7am in the first ,second and third days after surgery and 1 hours after surgery. Method of measurement: CR,BUN,K ,Cr CLEARANCE.;Clearance Cr. Timepoint: At 7am in the first ,second and third days after surgery and 1 hours after surgery. Method of measurement: : (140-age)× wt / 72× Pcr (in female × 0.85) = Cockroft.

Secondary Outcome Measures

Name	Time	Method
Check intake and output. Timepoint: during 8 pm to 8 am after operation and 24 hrs after 8 am. Method of measurement: by ICU sheet.