Impact and Utility of PET Versus Clinical Score for the Assessment of Inflammatory Activity in Takayasu Arteritis

Completed

• Conditions: Takayasu Arteritis

• Registration Number: NCT01532167
• Lead Sponsor: Instituto Nacional de Cardiologia Ignacio Chavez

Brief Summary

The purpose of this study is to demonstrate that \[18F\]FDG PET is a a better method than clinical and laboratory values for the identification and assessment of inflammatory activity in patients with Takayasu Arteritis (TA), allowing long-term follow-up with a precise evaluation of response to therapy.

Detailed Description

Inflammatory activity and fibrosis are the main causes of morbidity and mortality in patients with Takayasu arteritis. The investigators objective is to determine the utility of using 18F-FDG PET in the basal evaluation and follow-up of patients and compare the results with Dabague's clinical score.

Study Timeline

• Study Start: 2010-02
• Primary Completion: 2011-02
• Study Completion: 2011-02
• Study First Submitted: 2012-02-08
• Study First Submitted QC: 2012-02-13
• Study First Posted: 2012-02-14
• Status Verified: 2012-03
• Last Update Submitted: 2012-03-23
• Last Update Posted: 2012-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• TA was diagnosed if the patient met 3 or more ACR criteria.

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Instituto Nacional de Cardiologia; 🇲🇽 Mexico, DF, Mexico