Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Recruiting

• Conditions: Brain Metastases, Adult; Brain Tumor, Primary

• Registration Number: NCT05480644
• Lead Sponsor: Duke University

Brief Summary

The purpose of this protocol is to create a repository of blood samples from patients diagnosed with primary and metastatic brain tumors who are being seen in the Department of Radiation Oncology at Duke Cancer Center.

Detailed Description

Repository blood samples will be used to study the association of circulating biomarkers with radiation therapy outcomes.

Study Timeline

• Study First Submitted: 2022-07-27
• Study First Submitted QC: 2022-07-27
• Study First Posted: 2022-07-29
• Study Start: 2022-12-01
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-06
• Last Update Posted: 2025-01-07
• Primary Completion: 2032-12
• Study Completion: 2032-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of circulating immune cells in peripheral blood	6 weeks post radiation therapy	reported as mean +/- standard deviation

Trial Locations

Locations (1)

Duke Cancer Center; 🇺🇸 Durham, North Carolina, United States