Dual-focus Magnification With Narrow-band Imaging in Helicobacter Pylori Infection
- Conditions
- Helicobacter Pylori Infection
- Registration Number
- NCT03973242
- Lead Sponsor
- Kyunghee University Medical Center
- Brief Summary
Dual-focus with narrow-band imaging (DF-NBI) is a novel technique to improve the quality of images of the irregular mucosal structures and microvessels of gastric neoplasms. The investigators compare this technique with conventional white light (WL) endoscopy to predict Helicobacter pylori infection.
- Detailed Description
The subjects are patients who underwent upper gastrointestinal endoscopy under sedation. Participants are randomized into DF-NBI and WL groups. Rapid urease test will be performed in all cases. By captured images of gastric mucosa, classification of DF-NBI for Helicobacter pylori infected mucosa will be developed and validated. The established classification of WL for Helicobacter pylori infection will be used. Finally, the investigators will compare the accuracy between two groups based on each classification.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 292
- consecutive patients who have undergone uper gastrointestinal endoscopy for diagnosis or screening of cancer.
- Those whose Hp status had already been clarified
- Pregnancy
- History of partial gastrectomy
- Taking proton pump inhibitor, antithrombotics or antibiotics within 4 weeks
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Accurate prediction of Helicobacter pylori status 1 day Sensitivity, specificity, PPV, and NPV
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kyung Hee University Hospital
🇰🇷Seoul, Korea, Republic of
Kyung Hee University Hospital🇰🇷Seoul, Korea, Republic ofJae-Young Jang, MD, PhDContact82-2-958-8149Jung-Wook Kim, M.D., Ph.D.Principal Investigator