Effect of increasing lung pressure during anaesthesia for major operations of belly
Not Applicable
- Conditions
- Health Condition 1: K00-K95- Diseases of the digestive system
- Registration Number
- CTRI/2019/07/020009
- Lead Sponsor
- All India Institute Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status 1 and 2
Elective Major Abdominal Surgery( >2 hours) under General Anaesthesia
Exclusion Criteria
1.Patients rfefusal to participate in the study.
2.Patients undergoing emergency laparotomy.
3.Known COPD or chronic lung diseases.
4.Known deformity of chest wall or thoracic spine.
5.Pre-existing significant cardiac,renal, and hepatic diseases
6.intraoperative massive blood loss( loss > 40 ml/kg) or massive transfusion ( > 8 PRBCs transfused )
7.Patients on high dose ionotropes( Noradrenaline of 10 mcg/m or equivalent)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative atelectasis assessed by lung ultrasound in individualised PEEP titration group over fixed PEEP group.Timepoint: 10 minutes after extubation
- Secondary Outcome Measures
Name Time Method 1.Intraoperative and post operative oxygenation status(PaO2/FiO2) <br/ ><br> <br/ ><br>2.Post operative atelectasis(10 minutes after extubation) <br/ ><br> <br/ ><br>3.Incidence of intra operative bradycardia or hypotension <br/ ><br>4.Incidence of Post operative pulmonary complication by Melbourne Group Scale( upto 3 days of surgery) <br/ ><br> <br/ ><br>5.Number of patients needing supplemental oxygen to maintain SaO2 more than 95% <br/ ><br> <br/ ><br>6.Length of postoperative hospital stay. <br/ ><br>Timepoint: Intraoperative time till discharge of patient.