Study of the effect of Proton Pump Inhibitor (PPI) on intra-gastric pH in healthy volunteer - Comparison of Esomeprazole and Rabeprazole
Not Applicable
- Conditions
- Gastroesophageal reflux disease(GERD)
- Registration Number
- JPRN-UMIN000014577
- Lead Sponsor
- Shimane University Faculty of Medicine Second Department of Internal Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1.with taking drugs affecting gastrointestinal motor function 2.with a history gastrectomy 3.complicated with severe cardiac, hematologic, renal, hepatic diseases or malignant tumor 4.possibility to be pregnant or pregnant women 5.subjects who are not eligible for participation judged by a doctor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evaluation of intra-gastric pH following single oral pre- and postprandial administrations of esomeprazole and rabeprazole on 7th day
- Secondary Outcome Measures
Name Time Method