Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles
- Registration Number
- NCT04407065
- Lead Sponsor
- Riyadh Fertility and Reproductive Health center
- Brief Summary
The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in patients with history of poor oocytes yield, despite normal response to COH, due to low (\<50%) number of oocytes retrieved per number of follicles \> 14 mm in diameter on day of hCG administration
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 56
Inclusion Criteria
- Patients with history of poor oocytes yield in previous IVF attempt, despite normal response to COH, due to low (<50%) number of oocytes retrieved per number of follicles > 14 mm in diameter on day of hCG administration
- Patients with 6 to 15 mature follicles on the day oocyte trigger in the current IVF-ET attempt
Exclusion Criteria
- Endometriosis
- PCOS
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Double trigger Double trigger GnRH-agonist and HCG are used to trigger ovulation HCG HCG trigger HCG is used to trigger ovulation
- Primary Outcome Measures
Name Time Method Number of oocytes retrieved First day after oocyte retrieval
- Secondary Outcome Measures
Name Time Method clinical pregnancy rate First 5 weeks after oocyte retrieval The presence of gestational sac detected by ultrasound examination
Trial Locations
- Locations (1)
Riyadh Fertility and Reproductive Health center
🇪🇬Giza, Egypt