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临床试验/NCT03116490
NCT03116490招募中不适用

The Comparative Effects of Regional or General Anesthesia on the Prognosis of Hip Fracture Surgery on Elderly Patients

Wenzhou Medical University1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2026年1月16日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
600
试验地点
1
主要终点
Mortality

研究概览

简要总结

The aim of this study is to figure out whether anesthesia type have an influence on the prognosis of hip fracture surgery.30-day mortality and morbidity after the surgery are our main observational index,and according to literature and our experience,regional anesthesia may have a better prognosis after hip fracture surgery compared with general anesthesia.

详细描述

Hip fracture is a common disease among elderly people,and has a high mortality and morbidity.But,seldom practice can be done to improve this condition.For a long time,whether anesthesia type could influence the prognosis after surgery is controversial.Several studies have confirmed regional anesthesia may be better for patients for its fewer complications.But most studies are retrospective,and information may be less convincing .Besides,as a matter of fact,patients of different anesthesia type may have different status,so,a scoring system may be need for comparing the status of patients of different groups.

Our study is a prospective observational trial.Patients needing hip fracture surgery are divided into two groups according to the anesthesia type during surgery:Regional Anesthesia group(RA),General Anesthesia group(GA).To evaluate the status of patients before surgery,we use Orthopedic POSSUM scoring system.It consists of 12 physiological factors and 6 operative severity factors.Then,we will observe outcome of the two groups and record every complication after surgery.Finally,the initial and adjusted morbidity and mortality according to Orthopedic POSSUM scoring system of the two groups are compared.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with hip fracture;
  • Need surgery;
  • Anesthesia type is regional anesthesia or general anesthesia;
  • Age≥60 years.

排除标准

  • Choosing conservative treatment;
  • Other types of anesthesia or without anesthesia.

结局指标

主要结局

Mortality

时间窗: 30-day after surgery

次要结局

  • Morbidity(30-day after surgery)
  • VAS pain score(everyday after surgery,record for 7 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ting Li

Director,Associate chief physician of Anesthesia Department

Wenzhou Medical University

研究点 (1)

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