Glycemic and Insulinemic Response of Pasta Products in Comparison to Asian
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Glucose
研究概览
简要总结
The aim of the study is to determine the glycaemic and insulinaemic index of pasta products and local foods. It is hypothesized that different pasta cuts and wholegrain composition of pasta and local foods have different GI depending on the nature of the carbohydrate content and the food structure within each food.
详细描述
There will be a total of 9 test sessions and each session will last up to 3.5 hours. The order of sessions will be determined with an online randomizer. At each test session, the following procedures will be performed: two finger-prick blood samples, five minutes apart to measure baseline blood glucose and insulin concentrations Subject will be served the test food and to consume within15 minutes Following the test meal, blood samples will be collected at the following time points: 15, 30, 45, 60, 90, 120, 150 and 180min for glucose measurements and insulin measurements will be collected at 30, 60, 90, 120, 150 and 180min.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Asian - Indian and Chinese ethnicity
- •Age between 21-40 years
- •Body mass index between 18.5 to 25 kg/m2
- •Normal blood pressure (<140/90 mmHg)
- •Fasting blood glucose < 6 mmol/L
排除标准
- •Is a current smoker
- •Is currently pregnant
- •Have any metabolic diseases (such as diabetes, hypertension etc)
- •Have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
- •Have medical conditions and/or taking medications known to affect glycemia(glucocorticoids, thyroid hormones, thiazide diuretics)
- •Have any major organ dysfunction (e.g. cardiovascular, respiratory, hepatic, renal, gastrointestinal) that may influence taste, olfaction, appetite, digestion, metabolism, absorption or elimination of test foods, nutraceutical or drug
- •Have any severe food allergy (e.g. anaphylaxis to peanuts)
- •Have any known allergies to any food components of the study protocol
- •Have active Tuberculosis (TB) or currently receiving treatment for TB
- •Have any known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)
- •Is a study team member or an immediate family of any study team member. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted.
- •enrolled in a concurrent research study judged not to be scientifically or medically compatible with the study.
- •Have partake in sports at the competitive and/or endurance levels
- •Have intentionally restrict food intake
结局指标
主要结局
Glucose
时间窗: up to 180 minutes
Blood will be collected and measured using hemocue analyzer.
Insulin
时间窗: up to 180 minutes
Blood will be collected and measured using COBAS analyzer.
次要结局
未报告次要终点