Evaluation of Contrastmedium-Free Arterial Spin Labeling Magnetic Resonance Imaging (ASL-MRI) in the Detection of Pulmonary Artery Embolism: A Diagnostic Accuracy Study
- Conditions
- I26Pulmonary embolism
- Registration Number
- DRKS00023599
- Lead Sponsor
- niversitätsklinikum Tübingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 111
• Clinical suspicion of pulmonary artery embolism,
• Performing a CT-pulmonary angiography based on a clinical indication within the last 72 hours,
• Stable patient due to the medical assessment of the referring doctor,
• Age =18 years,
• Written consent from the patient.
• Presence of non-MR-compatible implants or any kind of metal in and on the body (e.g. pacemakers, artificial heart valves, metal prostheses, implanted, magnetic metal parts, coils, etc. that are not MR-compatible),
• People who report a hearing impairment or an increased sensitivity to loud noises,
• People with reduced temperature sensation and / or increased sensitivity to warming of the body,
• People who suffer from claustrophobia,
• Limited ability of the patient or test person to give consent,
• Obesity with a body weight of> 150 kg.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diagnostic accuracy of ASL-MRI with regard to detection / exclusion (positive or negative) of pulmonary artery embolism (sensitivity and specificity).
- Secondary Outcome Measures
Name Time Method • Creation of a qualitative assessment score of the image quality for the ASL-MRI,<br>• Comparison of the examination time of both procedures, ASL-MRT and CT-pulmonary angiography (each time start-end examination),<br>• Development of an ASL-MRI-based score for pulmonary artery embolism (quantitative lung perfusion index).