Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence
- Registration Number
- NCT00775879
- Lead Sponsor
- University Hospital, Bordeaux
- Brief Summary
Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 34
Inclusion Criteria
- programmed gynecological surgery
- ASA 1 or 2
Exclusion Criteria
- arterial hypertension
- gastro-oesophageal reflux
- pregnancy
- diabetes
- obesity
- asthma
- tobacco
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description A Induction with Sevoflurane 2.5% target concentration B Induction with Sevoflurane 2.5% manually selected
- Primary Outcome Measures
Name Time Method Incidence of spike wave during anaesthesia induction with sevoflurane
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link sevoflurane-induced spikes to EEG abnormalities in anesthesia?
How does target-controlled inhalation of sevoflurane compare to propofol for EEG spike suppression during induction?
Are specific biomarkers associated with sevoflurane-induced spike wave patterns in general anesthesia?
What adverse events are reported with sevoflurane mask induction and how are they managed clinically?
How do volatile anesthetics like sevoflurane interact with GABA receptors to influence spike wave activity?