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Clinical Trials/NCT02309723
NCT02309723
Completed
N/A

A Survey of Clinicians to Assess the Influence of Beta-amyloid Imagining Information on the Diagnosis and Management of Hypothetical Patients With Cognitive Complaints

Tufts Medical Center1 site in 1 country315 target enrollmentSeptember 2013

Overview

Phase
N/A
Intervention
Not specified
Conditions
Alzheimer's Disease
Sponsor
Tufts Medical Center
Enrollment
315
Locations
1
Primary Endpoint
Influence of the Neuroimaging Test on a Finding of Alzheimer's Disease as the Underlying Cause of the Mild Memory Loss
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

When older patients develop cognitive problems - like memory loss - there may be any of several underlying causes, sometimes occurring in combination. Clinicians have a better chance of providing appropriate treatment if they understand what the cause of the problem is. A diagnostic tool can help the patient by helping the clinician to make a more accurate diagnosis. This study investigates whether a new diagnostic tool - beta amyloid imaging - may potentially improve medical practice. The tool can potentially improve practice only if it can influence clinical judgment. This study investigates whether the provision of beta amyloid imaging information influences clinical judgment. The investigators will conduct a survey that presents clinicians with descriptions of hypothetical older patients with cognitive complaints. Some of the respondents also receive beta amyloid imaging information. The investigators will test the investigators hypothesis that the information will affect diagnostic judgment and management recommendations by comparing the responses of clinicians who receive the beta amyloid information to the responses of clinicians who do not.

Registry
clinicaltrials.gov
Start Date
September 2013
End Date
November 2013
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Practicing clinicians describing their training and practice as any of the following: neurologist, geriatrician, psychiatrist.
  • Included respondents must also attest that they are a physician who is experienced in the assessment and diagnosis of dementia.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Influence of the Neuroimaging Test on a Finding of Alzheimer's Disease as the Underlying Cause of the Mild Memory Loss

Time Frame: Online Survey - completion during the estimated 2-3 month field period

Proportion of respondents who identify Alzheimer's Disease as the sole or a contributing factor that is responsible for the patient's cognitive complaint.

Likelihood of Recommending a Medication Indicated for Alzheimer's Disease

Time Frame: Online Survey - completion during the estimated 2-3 month field period

Proportion of respondents who recommend a medication indicated for the treatment of Alzheimer's Disease, including Acetylcholinesterase inhibitors, N-methyl-D-aspartate receptor antagonists, Typical antipsychotics - e.g., Chlorpromazine (Thorazine), Haloperidol (Haldol), Atypical antipsychotics - e.g., Clozapine (Clozaril), Risperidone (Risperdal), Antidepressant - e.g., Citalopram (Celexa), Venlafaxine (Effexor), Antianxiety agent - e.g. Benzodiazepines, Buspirone (Buspar).

Likelihood of Recommending That Spouse Take Various Cognitive Deficit Disease Management Measures

Time Frame: Online Survey - completion during the estimated 2-3 month field period

Proportion of respondents who recommend that the patient's spouse take actions that would be appropriate if the patient has Alzheimer's disease, including: (1) discussion of advance care planning, (2) monitoring of patient's finances, (3) assessment of how compatible the patient's job is with his conditions, (4) the initiation of precautions to ensure the patient is properly taking his medications to manage hypertension and hyperlipidemia.

Study Sites (1)

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