The Effect of Ibuprofen Sustained Release Oral Premedication on Intraoperative and Postoperative Pain After Single-visit Root Canal Treatment of Mandibular Molars With Symptomatic Irreversible Pulpitis and Apical Periodontitis
Overview
- Phase
- Not Applicable
- Intervention
- Brufen Retard
- Conditions
- Anesthesia
- Sponsor
- Cairo University
- Enrollment
- 48
- Primary Endpoint
- Efficacy of buccal infiltration anaesthesia measured using Visual analogue scale
- Last Updated
- 4 years ago
Overview
Brief Summary
The study is conducted to evaluate the effect of Ibuprofen sustained release premedication on the success of buccal infiltration anaesthesia, intaroperative pain and post operative pain in mandibular molars with symptomatic irreversible pulpitis and apical periodontitis
Investigators
Mariam Ahmed Hossam
Resident at faculty of dentistry, Cairo University
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Systemically healthy patients (ASA I or II).
- •Patients with Mandibular molar teeth diagnosed with:
- •Pre-operative sharp pain marked on VAS scale by reading not less than
- •Vital exaggerated response of pulp tissue to cold pulp tester (ethyl chloride spray) and electric pulp tester.
- •Normal periapical radiographic appearance or slight widening in lamina dura.
- •Positive response and pain provoked by percussion.
Exclusion Criteria
- •Allergy to Ibuprofen
- •Medically compromised patients having significant systemic disorders. (ASA III or IV).
- •History of intolerance to NSAIDS.
- •Patients with two or more adjacent teeth requiring endodontic treatment.
- •Pregnant or nursing females.
- •Teeth that have:
- •Periodontal affection (with pocket depth greater than 5mm, associated with swelling or fistulous tract, or greater than grade I mobility)
- •No possible restorability.
Arms & Interventions
Ibuprofen sustained release
Single dose of 800 mg Brufen Retard oral premedication will be administered 1 hour before local anesthesia
Intervention: Brufen Retard
Placebo
1 capsule of 500 mg of glucose oral premedication will be adminstered 1 hour before local anesthesia
Intervention: Brufen Retard
Outcomes
Primary Outcomes
Efficacy of buccal infiltration anaesthesia measured using Visual analogue scale
Time Frame: During root canal treatment procedures
intensity of pain during root canal treatment procedures is recorded by the patient using VAS where 0=no pain, 1-3=mild pain, 4-6=moderate pain and 7-10=severe pain
Secondary Outcomes
- Intensity of intraoperative pain(During root canal treatment procedures)
- Number of needed analgesic tablets in case of intolerable pain(up to 48 hours after endodontic treatment)
- Postoperative pain(up to 48 hours after endodontic treatment)