Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth

Not Applicable

• Conditions: Preemptive Intravenous Ibuprofen; Intraoperative Analgesia
• Interventions: Drug: arveles; Drug: intrafen 800 mg; Other: plasebos

• Registration Number: NCT03170726
• Lead Sponsor: Erzincan University

Brief Summary

This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Status Verified: 2017-05
• Study Start: 2017-05-15
• Study First Submitted: 2017-05-20
• Study First Submitted QC: 2017-05-26
• Last Update Submitted: 2017-05-26
• Study First Posted: 2017-05-31
• Last Update Posted: 2017-05-31
• Primary Completion: 2017-10-30
• Study Completion: 2017-11-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients who are to be elected third molar tooth extraction
• Patients between the ages of 20-35
• Patients who are symptomatic
• Third molar tooth angular or horizontal settled patients

Read More

Exclusion Criteria

• Patients who refuse to participate in the study
• Patients under 20 years old, over 35 years old
• Patients who are allergic to known non-steroidal anti-inflammatory drugs
• Pregnant patients
• Patients with severe liver failure,
• patients with severe renal insufficiency

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
arveles	plasebos	Ibuprofen 800 mg in normal saline 150 cc and dexketoprofen (50 mg) before operation will be given in 30 minutes
arveles	arveles	Ibuprofen 800 mg in normal saline 150 cc and dexketoprofen (50 mg) before operation will be given in 30 minutes
arveles	intrafen 800 mg	Ibuprofen 800 mg in normal saline 150 cc and dexketoprofen (50 mg) before operation will be given in 30 minutes
intrafen	arveles	intrafen 800 mg in normal saline 150 cc before operation will be given in 30 minutes
intrafen	intrafen 800 mg	intrafen 800 mg in normal saline 150 cc before operation will be given in 30 minutes
intrafen	plasebos	intrafen 800 mg in normal saline 150 cc before operation will be given in 30 minutes
plasebos	arveles	150 cc normal saline will be given in 30 minutes during preoperative period
plasebos	intrafen 800 mg	150 cc normal saline will be given in 30 minutes during preoperative period
plasebos	plasebos	150 cc normal saline will be given in 30 minutes during preoperative period

Primary Outcome Measures

Name	Time	Method
intraoperative pain as assessed by visual analogue scale	5 month	Assessment of Preemptive intravenous ibuprofen on intraoperative analgesic efficacy in 3. molar tooth extraction

Secondary Outcome Measures

Name	Time	Method
postoperative pain as assessed by visual analogue scale	5 month	postoperative analgesic contribution of preemptively administered intravenous ibuprofen.

Trial Locations

Locations (1)

Erzincan University; 🇹🇷 Erzincan, Turkey