Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Edema size measured by tape measure method
研究概览
简要总结
this study was planned to investigate the antiinflammatory activity of preemptive intravenous ibuprofen on inflammatory complications such as edema and trismus after third molar tooth surgery
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Molar tooth extraction
- •Patients between the ages of 20-35
- •Patients who are symptomatic
- •Molar tooth angular or horizontal settled patients
排除标准
- •Patients who refuse to participate in the study
- •Patients under 20 years old, over 35 years old
- •Patients who are allergic to known non-steroidal anti-inflammatory drugs
- •Pregnant patients
- •Patients with severe hepatic insufficiency
- •Patients with severe renal insufficiency
研究组 & 干预措施
arveles
800 mg ibuprofen and 50 mg arveles in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: arveles (Drug)
arveles
800 mg ibuprofen and 50 mg arveles in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: intrafen (Drug)
arveles
800 mg ibuprofen and 50 mg arveles in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: placebos (Other)
intrafen
intrafen 800 mg in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: arveles (Drug)
intrafen
intrafen 800 mg in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: intrafen (Drug)
intrafen
intrafen 800 mg in 150 cc normal saline before operation will be given in 30 minutes.
干预措施: placebos (Other)
placebos
Pre-operative 150 cc normal saline will be delivered in 30 minutes
干预措施: arveles (Drug)
placebos
Pre-operative 150 cc normal saline will be delivered in 30 minutes
干预措施: intrafen (Drug)
结局指标
主要结局
Edema size measured by tape measure method
时间窗: 6 month
the effect of preemptive intravenous ibuprofen on postoperative edema size
次要结局
- Maximum mouth opening measured with vernier caliper(6 month)
研究者
ILKE KUPELI
assist. prof.
Erzincan University