Satiety Response of Short Chain Fructooligosaccharide
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Satiety response using visual analogue scales
研究概览
简要总结
Populations that report high fiber consumption demonstrate lower rates of obesity. Enhanced satiety may play a key role in this relationship. The colonic fermentation of fibers is theorized to influence satiety and food intake. Short chain fructooligosaccharide (scFOS) are rapidly fermentable fibers that can easily be added to foods to impact these parameters.
The objective of this study was to evaluate the satiety response of scFOS and its ability to decrease food intake.
详细描述
Intervention study with fiber added to beverages and acute effects on satiety measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men and women
- •Age 18-64 years
- •Non-smoking
- •Not taking medication
- •Non-dieting (weight stable in prior 3 months)
- •BMI 18-27
- •English literacy
排除标准
- •Do not regularly consume breakfast
- •Food allergies to ingredients found in study products
- •BMI <18 or >27
- •Diagnosed cardiovascular, renal, or hepatic disease diabetes mellitus
- •Cancer in previous 5 years (except basal cell carcinoma of the skin)
- •Any gastrointestinal disease or condition
- •Recent bacterial infection (< 3 months)
- •Recent or concurrent participation in an intervention research study
- •History of drug or alcohol abuse in prior 6 months
- •Use of lipid-lowering, anti-hypertensive, or anti-inflammatory steroid medication
- •Eating disorder
- •Vegetarians
- •People who eat more than approximately 15 grams of fiber per day
- •Women who are pregnant or lactating
- •Women with irregular menstrual cycles
结局指标
主要结局
Satiety response using visual analogue scales
时间窗: 0, 15, 30, 45, 60, 90, 120, 180, 240 minutes postprandially
Satiety response was measured using subjective perceptions of hunger, fullness, satisfaction, and prospective food intake evaluated by previously validated visual analogue scales (VAS).
次要结局
- Ad libitum food intake(240 minutes postprandially and over 24 hours)
- Breath hydrogen response(0, 240 minutes)
- Gastrointestinal tolerance using visual analogue scales (VAS)(24 hours)