Desensitizing Effect and Tooth Color Change After Using Giomer-based Varnish Versus Bioactive Glass Air Polishing in Treating Cervical Hypersensitive Lesions

Not Applicable

Not yet recruiting

• Conditions: Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG

• Registration Number: NCT05981625
• Lead Sponsor: Cairo University

Brief Summary

This trial is test the dentin hypersenstivity using Giomer based Varnish versus Bioactive glass air polishing system in patients with non-cervical lesions.

Detailed Description

To investigate the clinical effectiveness of Giomer based varnish versus Bioactive glass air polishing System in the management of dentin hypersensitivity and tooth color change in the cervical lesions.

P:Patient/Population: Middle aged patients complaining of cervical dentin hypersensitivity. I: Giomer varnish containing surface pre-reacted glass fillers. C: Bio-active glass air polishing system: O:Dentin Hypersenstivity (Primary Outcome) was assessed by three different stimuli (evaporative , thermal and tactile) . O: Color Change (Secondary Outcome). T: Baseline, T1, T2, T3. S:a randomized clinical trial.

Study Timeline

• Status Verified: 2023-07
• Study First Submitted: 2023-07-31
• Study First Submitted QC: 2023-07-31
• Last Update Submitted: 2023-07-31
• Study First Posted: 2023-08-08
• Last Update Posted: 2023-08-08
• Study Start: 2024-04
• Primary Completion: 2025-06
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Participants complaining from dentin hypersensitivity.
• Middle aged patients.
• Good oral hygiene.

Exclusion Criteria

• Pregnant women.
• Patients with allergy to any material used in this study.
• Smoking patients will affect the oral hygiene and periodontal health.
• Patients taking anti-inflammatory drugs that will affect the perception of hypersensitivity.
• Systemically compromised patients.
• Smokers.
• Patients received desensitization treatment in the last 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pain due to dentin hypersenstivity	baseline preoperative, immediate postoperative, 1 , 6 and 12-months' time	Dentin hypersensitivity was assessed by three different stimuli (evaporative , thermal and tactile) to simulate the different situations in which Dentin hypersensitivity arises. Using the Visual Analog scale (VAS), the participant marks the pain intensity on a graduated 10 cm straight line (0; = no pain, 10 = extreme pain)

Secondary Outcome Measures

Name	Time	Method
Color change (Tooth discoloration)	Baseline preoperative, immediate postoperative, 1,6 and 12-months time	According to USPH criteria Alpha: Matches tooth Bravo: Acceptable mismatch Charlie: Unacceptable mismatch