Interest of the T2 * Sequence in MRI for the Diagnosis of Migraine Aura in the Acute Phase.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- frequency of the presence of visible brain vein abnormalities
研究概览
简要总结
investigators hypothesize that T2 * vein abnormalities are frequent and are specific to the migraine aura.
详细描述
The diagnosis of migraine aura is now based solely on clinical criteria and the assertion of the diagnosis on these clinical criteria alone proves difficult in the acute phase. Added to this difficulty, the symptomatology of a migraine aura can sometimes be similar to that of a stroke, so a diagnosis can be poorly established, resulting in poor patient care. The possibility of making the positive diagnosis of migraine aura on a routine MRI sequence, T2 *, would be an important advance for the management of these patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 55 years
- •Admitted to the Neuro-Vascular Intensive Care Unit for Acute Focused Neurological Symptoms and MRI
- •less than 4 hours 30 minutes after onset of symptoms if symptoms persist during admission
- •less than two hours after the disappearance of symptoms if the patient arrives asymptomatic
- •Affiliated to a social protection scheme.
- •Having given their informed consent
排除标准
- •Patients with neurological signs pointing to vertebrobasilar localization (vertigo, diplopia) or with a disorder of consciousness
- •Presence of recent explanatory abnormalities on the MRI to make a diagnosis compatible with the initial neurological symptomatology (visible stroke in diffusion, cerebral hemorrhage, tumor, arteriovenous malformations).
- •Potential strong cause of stroke known or discovered at the arrival of the patient, in particular stenosis of a cervical or intracranial artery upstream of the cerebral zone may correspond to the symptoms and emboligenic heart disease type atrial fibrillation.
- •Pregnant women - Patients with a contraindication for MRI.
- •Patients benefiting from a system of legal protection (tutelage,
结局指标
主要结局
frequency of the presence of visible brain vein abnormalities
时间窗: Day 0
visible brain vein abnormalities on T2 \* sequences MRI ,
次要结局
- asymmetry of visualization of the 3 intracranial arteries in MRI(Day 0)
- perfusion parameters(Day 0)