CLINICAL STUDY TO COMPARE THE EFFECT OF FENTANYL AND DEXMEDETOMIDINE AS AN ADJUVANT TO 05% BUPIVACAINE IN NERVE STIMULATOR GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK FOR UPPER LIMB SURGERIES
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To compare the efficacy of 0.5% Bupivacaine with dexmedetomidine, 0.5% Bupivacaine with fentanyl and 0.5% Bupivacaine innerve stimulator guided supraclavicular brachial plexus block.
研究概览
简要总结
Variousclinical trials have found that administration of dexmedetomidine and fentanylwith local anaesthetics in neuraxial and peripheral nerve blocks prolonged theduration of sensory and motor blockade.
However, there arelimited data available on comparing of dexmedetomidine and fentanyl as adjuvantto Bupivacaine in brachial plexus block. Considering the low side effect andexcellent postoperative analgesic efficacy of two drugs, it is essential tocarry out a comparative evaluation of two drugs for their use with bupivacaine asadjuvant in patients undergoing upper limb surgeries which requiresupraclavicular brachial plexus block. To compare whether adding dexmedetomidineand fentanyl to bupivacaine for supraclavicular brachial plexus block wouldaffect the sensory and motor blocks and duration of analgesia. The present work has been undertaken to studyand compare the effect provided by dexmedetomidine and fentanyl as adjuvants tobupivacaine in supraclavicular block.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age18 years.
- •ASA grade 1 and
- •Scheduled for elective upper limb surgeries under supraclavicular brachial plexus block.
排除标准
- •Lack of patient’s consent.
- •Age <18yrs and >60yrs.- ASA grade 3 and more.
- •History of serious pulmonary disease, ischemic heart disease, renal/hepaticdysfunction, coronary artery, or cervical spine disease and patients with abnormal coagulation profile.
- •Patient with h/o opioid abuse.
- •Patients with hypersensitivity to any of the drugs used.
- •Pregnant and lactating mothers.
- •Failure of Block.
- •Restricted neck movement.
结局指标
主要结局
To compare the efficacy of 0.5% Bupivacaine with dexmedetomidine, 0.5% Bupivacaine with fentanyl and 0.5% Bupivacaine innerve stimulator guided supraclavicular brachial plexus block.
时间窗: First 24 hours at 5 mins, 10 mins, 15 mins, 30 mins, 1 hour, 2 hour, 4 hours, 6 hours, 12 hours and 24 hours
次要结局
- To compare side effects of 0.5% Bupivacaine with dexmedetomidine, 0.5% Bupivacaine with fentanyl and 0.5% Bupivacaine innerve stimulator guided supraclavicular brachial plexus block.(First 24 hours at 5 mins, 10 mins, 15 mins, 30 mins, 1 hour, 2 hour, 4 hours, 6 hours, 12 hours and 24 hours)