Effect of chronic garlic intake on platelet functio
Phase 1
- Conditions
- improvement in overall health status by garlic and preoperative setting
- Registration Number
- EUCTR2007-004208-11-AT
- Lead Sponsor
- Medizinische Universität Wien, Univ.-Klinik für Spezielle Anästhesie und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
healthy volunteers
ASA I and II
age > 18 and < 65 years
no medication
normal platelet function at baseline
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years)
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
contraindications against Kwai or Voltaren
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: chronic garlic intake (Kwai) inhibits platelet function assessed by impedance aggregometry, Platelet Mapping assay and PFA-100;Secondary Objective: chronic garlic intake potentiates platelet-inhibiting effects of diclofenac (Voltaren);Primary end point(s): garlic decreases the area under the aggregation curve (AUC) in arachidonic acid-induced impedance aggregometry
- Secondary Outcome Measures
Name Time Method