Garlic supplementation in patients with diabetic nephropathy

Not Applicable

Recruiting

• Conditions: Diabetic nephropathy.; Type 2 diabetes mellitus with kidney complications; E11.2

• Registration Number: IRCT20171107037302N3
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Diagnosis of diabetic nephropathy confirmed by a specialist - - being in the age range of 25 to 75 years
clinically in stage 3 (eGFR equivalent to 30 to 59) or stage 4 (eGFR equivalent to 15 to 29) chronic kidney disease
age 25-75 years old

Exclusion Criteria

not performing hemodialysis or peritoneal dialysis
presence of liver, gastrointestinal, stroke and ischemic heart disease (3 months after stroke and ischemic heart disease), pulmonary disease (asthma and COPD), cancer, hypothyroidism and hyperthyroidism, gastric ulcer, infectious especially hepatitis, garlic allergy
No pregnancy and lactation
not consuming drugs of anticoagulants such as heparin, warfarin, apixaban, uvaroxaban, penicillamine and 3 months after taking antibiotics
No history of taking garlic supplements and no special diet in the last 3 months
Not smoking

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Weight. Timepoint: Beginning of study - week 8. Method of measurement: Digital scales.;Waist circumference. Timepoint: Beginning of study - week 8. Method of measurement: strip meter.;Body mass index. Timepoint: Beginning of study - week 8. Method of measurement: formula.;Mild arm circumference. Timepoint: Beginning of study - week 8. Method of measurement: stripe meter.;Fasting blood sugar. Timepoint: Beginning of study - week 8. Method of measurement: biochemical assesment.;Triglycerides. Timepoint: Beginning of study - week 8. Method of measurement: biochemical assessment.;Low density lipoprotein- cholesrtol. Timepoint: Beginning of study - week 8. Method of measurement: formula.;High density lipoprotein-cholestrol. Timepoint: Beginning of study - week 8. Method of measurement: biochemical assessment.;Total cholestrol. Timepoint: Beginning of study - week 8. Method of measurement: biochemical assessment.;Fasting insulin. Timepoint: Beginning of study - week 8. Method of measurement: biochemical assessment.

Secondary Outcome Measures

Name	Time	Method
Estimated glomerular filtration rate. Timepoint: Beginning of the study - week 8. Method of measurement: Formula.;Blood urea nitrogen. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.;Creatinine. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.