Garlic supplementation in patients with diabetic nephropathy

Not Applicable

Recruiting

• Conditions: Diabetic nephropathy.; Type 2 diabetes mellitus with kidney complications; E11.2

• Registration Number: IRCT20130903014551N11
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Diagnosis of diabetic nephropathy confirmed by a specialist
age 25-75 years old
being in the age range of 25 to 75 years clinically in stage 3 (eGFR equivalent to 30 to 59) or stage 4 (eGFR equivalent to 15 to 29) chronic kidney disease

Exclusion Criteria

not performing hemodialysis or peritoneal dialysis
presence of liver, gastrointestinal, stroke and ischemic heart disease (3 months after stroke and ischemic heart disease), pulmonary disease (asthma and COPD), cancer, hypothyroidism and hyperthyroidism, gastric ulcer, infectious especially hepatitis, garlic allergy
No pregnancy and lactation
not consuming drugs of anticoagulants such as heparin, warfarin, apixaban, uvaroxaban, penicillamine and 3 months after taking antibiotics
No history of taking garlic supplements and no special diet in the last 3 months
Not smoking

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total antioxidant capacity (TAC). Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Super oxide dismutase. Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Malon di aldehyde. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.;(CRP) C-reactive protein. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.