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Effect Of Garlic In Knee osteoarthrosis

Not Applicable
Conditions
Knee Osteoarthritis.
Gonarthrosis [arthrosis of knee]
Registration Number
IRCT201204239543N1
Lead Sponsor
Tehran University Of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
80
Inclusion Criteria

women; 50-75 years old; postmenopausal; obese body mass index between 25 - 35 with moderate and severe knee osteoarthritis Diagnosis by rheumatologist.
Exclusion criteria:severe pain or hip involvement; candidate for surgery; had a knee sergery; sensitivity of garlic; smoking; history of cardiovascular disease; type 1 diabetes; liver disease; hypo or hyper thyroid; kidney disease; arthritis; gout; cancer; any injection in knee in 3 month before intervention; intake of NSAIDs; HRT; astatine; warfarin and supplement like omega 3 or 6 and condroitin sulphate; being in a diet or weight loss about 5% during 3 month in this study.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Resistin. Timepoint: Week 12. Method of measurement: Lab kit.;Tumor Necrosis Factor-Alpha. Timepoint: Week 12. Method of measurement: kit.
Secondary Outcome Measures
NameTimeMethod
Body Composition (Fat mass, Fat Free Mass). Timepoint: Week 12. Method of measurement: Bio Electrical Impedance.;Fasting Blood Sugar. Timepoint: Week 12. Method of measurement: ELISA kit.;Weigth. Timepoint: Week 12. Method of measurement: Balance.
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