Analgesic drug combinations in post-operative movement-evoked pai

Completed

• Conditions: Post-operative pain; Surgery

• Registration Number: ISRCTN33126288
• Lead Sponsor: Physician's Services Incorporated (PSI) Foundation (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-05-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

1. Patients aged 18 or older (either sex) requiring elective laparoscopic cholecystectomy
2. American Society of Anesthesiologists class 1 or 2
3. Body mass index (weight in kilograms/[height in meters]^2) less than or equal to 35

Exclusion Criteria

1. Known history of hypersensitivity to any agents to be used in the study
2. History of serious organ disease/dysfunction
3. History of persistent pain (excluding gallbladder pain) prior to surgery
4. Daily intake, or intake within 48 hours prior to surgery, of any glucocorticoid agents, non-steroidal anti-inflammatory agents, or other analgesics, not including daily administration of less than or equal to 325 mg of aspirin for cardiovascular prophylaxis
5. History or evidence of substance or alcohol abuse
6. History of a major psychiatric disorder
7. History of a bleeding disorder
8. History of peptic ulcer disease
9. History of moderate to severe asthma with forced expiratory volume in 1 second (FEV1) less than 65% predicted
10. History of a seizure disorder requiring treatment with an anticonvulsant drug
11. A language barrier in communicating with research staff

Study & Design

• Study Type: Interventional
• Study Design: Not specified