Memantine effect on pain tolerance time in MMTP patients
Phase 3
- Conditions
- pain tolerance time.
- Registration Number
- IRCT20090801002266N17
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
Undertreatment in MMT program for at least 6 months
No methadone dose modification in recent 6 months
Exclusion Criteria
Any analgesic medication use
Sedative drugs use
Substance use disorder
Any kind of psychiatric disorders
Any kind of neuropathy, Raynaud’s disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean threshold of pain in cold pressor test. Timepoint: In the beginning of study and after 5 weeks of memantine or placebo. Method of measurement: Cold peressor test; stopwatch.;Mean duration of maximum pain tolerance in Cold pressor test. Timepoint: In the beginning of the study and after 5 weeks of memantine or placebo administration. Method of measurement: Cold professor test will be performed for patients and the time of onset of pain and maximum pain tolerance will be measured with a stopwatch.
- Secondary Outcome Measures
Name Time Method