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Optimising the effects of exercise in diabetes

Withdrawn
Conditions
Diabetes
10011082
10012653
10003216
Registration Number
NL-OMON36171
Lead Sponsor
niversitair Medisch Centrum Sint Radboud
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

Older than 40 years
Diagnosed with type 2 diabetes mellitus at least 2 years ago

Exclusion Criteria

Women
Cardiovascular disease
Hypercholesterolemia
Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs
Smoking
Type I diabetes mellitus
Older than 65 years
Subjects with vascular complications due to type 2 diabetes mellitus (e.g. diabetic foot ulcer)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The effect of an increase in the exercise-induced shear stress on the<br /><br>post-exercise endothelial function (as measured with the brachial artery<br /><br>flow-mediated dilation) in subjects with T2DM<br /><br>The effect of hyperglycaemia on post-exercise endothelial function (as measured<br /><br>with the brachial artery flow-mediated dilation) in T2DM.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Not applicable</p><br>
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