Optimization of exercise therapy in type 2 diabetes mellitus - Hypo- and hyperoxic exercise & glycemic profile in DM2

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sponsor

•Diabetes patients(n\=12\):
•Type 2 Diabetes Mellitus \>3 months.
•Age: 40\-65 years.
•BMI between 27 and 35 kg/m2\.
•Formal permission to participate in the study by signing an informed consent form.
•Healthy subjects(n\=20\):
•Age:18\-40 years.
•BMI:23\-26 kg/m2
•Formal permission to participate in the study by signing an informed consent form.
•Overweight /Obese subjects \- glucosetolerant(n\=12\):

•Cardiovascular disease: objective heart failure (ejection fraction \<35%), electrocardiographically diagnosed cardiac ischemia or symptomatic peripheral vascular disease diagnosed by Doppler ultrasound investigation
•Serious orthopedic of neurological conditions precluding an exercise test.
•Healthy subjects:
•Positive signs of cardiac ischaemia on the ECG (ST\>2mm) during the incremental exercise test;
•Orthopaedic impairments that would limit participation in the study.
•Obese volunteers \- glucose tolerant:
•Positive signs of cardiac ischaemia on the ECG (ST\>2mm) during the incremental. exercise test;
•Orthopaedic impairments that would limit participation in the study.
•Use of β\-blockers, a\-blockers, calcium antagonists.
•Obese volunteers \- glucose intolerant: