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Efficacy of midazolam on blood pressure control

Phase 2
Recruiting
Conditions
Crease blood pressure.
Essential (primary) hypertension
Registration Number
IRCT20181010041299N1
Lead Sponsor
Shahroud University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
129
Inclusion Criteria

Systolic or diastolic blood pressure above 180 on 110 mm Hg
age group is 18-18 years old
Have the power to understand and sign a conscientious informed consent

Exclusion Criteria

Chronic renal failure
Cardiovascular disease
History of stroke
History of myocardial infarction
Benzodiazepines consumed in the last week
Use of muscle relaxants such as baclofen or anti-anxiety drugs Other groups such as zoolpidum or baspirone
Acute left heart failure
Captopril susceptibility
Sensitivity to midazolam
Sensitivity to midazolam
Pregnant and lactating women
The occurrence of a critical condition, according to the doctor's opinion, requires the administration of a blood pressure lowering medication other than midazolam and captopril
Patients with a difference between the two arms are more than 15 mm Hg

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Systolic or diastolic blood pressure. Timepoint: Blood pressure measurement at the beginning of the study and 10 minutes after (before the intervention). Then at 15, 30, 45 and 60 minutes after the intervention. Method of measurement: How to measure blood pressure in a standardized manner using a mercurial barometric device.
Secondary Outcome Measures
NameTimeMethod
Sleepiness rate. Timepoint: 15, 30, 45 and 60 minutes after intervention. Method of measurement: Examination by a specialist.;Shortness of breath. Timepoint: 15, 30, 45 and 60 minutes after intervention. Method of measurement: Examination by a specialist.
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