The effect of low dose of midazolam on blood pressure and anxiety scale in white-coat hypertensive dental patients: a double-blind randomized controlled trial.
Not Applicable
- Conditions
- Dental patients
- Registration Number
- JPRN-UMIN000007066
- Lead Sponsor
- Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1.Uncontrolled or unstable hypertension 2.Secondary hypertension such as hyperthyroidism and pheochromocytoma 3.Taking sympathomimetic drugs 4.Contraindication of midazolam such as myasthenia gravis and acute narrow-angle glaucoma 5.A pregnant woman or during lactation period 6.Psychiatric disorder such as schizophrenia 7.Not having intelligence enough to read, understand and write a Japanese version of STAI 8.Judged unsuitable by a researcher
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure, heart rate, and oxygen saturation before and 2,4,6,8,10 minutes after drug administration. Japanese version of STAI before and 10 minutes after drug administration.
- Secondary Outcome Measures
Name Time Method Visual analog scale about anxiety to dental treatment. Sedation level.