To study changes in finger blood flow and blood pressure during placement and removal of tube in windpipe under general anaesthesia

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/09/057290

Lead Sponsor: Safdarjung Hospital

Brief Summary: The Perfusion index (PI) isa continuous, non-invasive, cost effective, indirect measure of peripheralperfusion, monitored by photoplethysmography. It has been suggested that PI canbe used as a complimentary haemodynamic parameter for early detection of haemodynamicinstability in trauma and critically ill patients, in lieu of it being avaluable adjunct for early detection of acute hemodynamic responses to centralhypovolemia. Stress response during intubation and extubation during generalanaesthesia is known to cause a change in the peripheral vasomotor tone,leading to haemodynamic changes. There is an associated increase in heart rate(HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and meanarterial pressure (MAP). This increase in the peripheral vasomotor tone, leadsto a decrease in peripheral perfusion, and is thereby, expected to cause anassociated fall in the PI. Thereis paucity of literature with regard to changes in perfusion index andhaemodynamic parameters during tracheal intubation and extubation in adultpatients undergoing elective surgery under general anaesthesia. Our studyhypothesis is that perfusion index changes with haemodynamicparameters during tracheal intubation and extubation in adult patients undergoingelective surgery under general anaesthesia. The aim of our study is to study changesin perfusion index and haemodynamicparameters during tracheal intubationand extubation in adult patients undergoing elective surgery under generalanaesthesia.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 45

Inclusion Criteria

Adult patients, aged 18.
65 years, belonging to American Society of Anesthesiologists Physical Status I scheduled for elective surgery under general anaesthesia with tracheal intubation.

Exclusion Criteria

1.Patients with cardiovascular disease, hepatic or renal disease or diabetes mellitus 2.Anticipated difficult airway 3.Perioperative use of vasopressor.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study the changes in perfusion index during tracheal intubation & extubation in adult patients undergoing elective surgery under general anaesthesia using pulse oximeter	0,1,2,3,4,5,6,7,8,9, 10 min intubation \| 0,1,2,3,4,5 min extubation

Secondary Outcome Measures

Name	Time	Method
1.To study the haemodyanamic parameters (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, oxygen saturation) during tracheal intubation & extubation	2.To correlate changes in perfusion index with changes in haemodynamic parameters during tracheal intubation and extubation

Trial Locations

Locations (1): Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi
🇮🇳
South, DELHI, India
Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi
🇮🇳South, DELHI, India
Dr Smita Prakash
Principal investigator
drsunilprakash@gmail.com