跳至主要内容
临床试验/CTRI/2023/09/057290
CTRI/2023/09/057290尚未招募不适用

Assessment of variations in perfusion index derived from photoplethysmography during tracheal intubation and extubation in adult patients undergoing elective surgery

Safdarjung Hospital1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2023年9月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
45
试验地点
1
主要终点
To study the changes in perfusion index during tracheal intubation & extubation in adult patients undergoing elective surgery under general anaesthesia using pulse oximeter

研究概览

简要总结

The Perfusion index (PI) isa continuous, non-invasive, cost effective, indirect measure of peripheralperfusion, monitored by photoplethysmography. It has been suggested that PI canbe used as a complimentary haemodynamic parameter for early detection of haemodynamicinstability in trauma and critically ill patients, in lieu of it being avaluable adjunct for early detection of acute hemodynamic responses to centralhypovolemia. Stress response during intubation and extubation during generalanaesthesia is known to cause a change in the peripheral vasomotor tone,leading to haemodynamic changes. There is an associated increase in heart rate(HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and meanarterial pressure (MAP). This increase in the peripheral vasomotor tone, leadsto a decrease in peripheral perfusion, and is thereby, expected to cause anassociated fall in the PI. Thereis paucity of literature with regard to changes in perfusion index andhaemodynamic parameters during tracheal intubation and extubation in adultpatients undergoing elective surgery under general anaesthesia. Our studyhypothesis is that perfusion index changes  with haemodynamicparameters during tracheal intubation and extubation in adult patients undergoingelective surgery under general anaesthesia. The aim of our study is to study changesin  perfusion index and haemodynamicparameters   during tracheal intubationand extubation in adult patients undergoing elective surgery under generalanaesthesia.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Adult patients, aged
  • 65 years, belonging to American Society of Anesthesiologists Physical Status I scheduled for elective surgery under general anaesthesia with tracheal intubation.

排除标准

  • 1.Patients with cardiovascular disease, hepatic or renal disease or diabetes mellitus 2.Anticipated difficult airway 3.Perioperative use of vasopressor.

结局指标

主要结局

To study the changes in perfusion index during tracheal intubation & extubation in adult patients undergoing elective surgery under general anaesthesia using pulse oximeter

时间窗: 0,1,2,3,4,5,6,7,8,9, 10 min intubation | 0,1,2,3,4,5 min extubation

次要结局

  • 1.To study the haemodyanamic parameters (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, oxygen saturation) during tracheal intubation & extubation(2.To correlate changes in perfusion index with changes in haemodynamic parameters during tracheal intubation and extubation)

研究者

申办方类型
Government medical college

研究点 (1)

Loading locations...

相似试验