Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children

Not Applicable

Completed

• Conditions: Dental Caries; Dental Plaque
• Interventions: Other: Novamin containing toothpaste; Other: Fluoride containing toothpaste

• Registration Number: NCT05979636
• Lead Sponsor: Hams Hamed Abdelrahman

Brief Summary

Inhibition of streptococcus mutans can be effective to prevent caries in high caries-risk children. The aim of the study is to evaluate the effect of Novamin on streptococcus mutans in the plaque of high caries-risk children.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-06
• Primary Completion: 2023-01-01
• Study Completion: 2023-01-01
• Status Verified: 2023-07
• Study First Submitted: 2023-07-29
• Study First Submitted QC: 2023-07-29
• Last Update Submitted: 2023-07-29
• Study First Posted: 2023-08-07
• Last Update Posted: 2023-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Medically healthy children.
• No erupting first permanent molars.
• High caries risk children; Have visible cavities or have a visible plaque on their teeth.
• Cooperative (Positive or definitely positive), according to Frankl's Behavior Rating Scale

Exclusion Criteria

• History of intake of antibiotics for the past 3-4 weeks.
• History of professional fluoride treatment over 2 weeks before the study.
• Children with tooth structure defects.
• Children unable to return for recall visits

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Test group	Novamin containing toothpaste	-
Control group	Fluoride containing toothpaste	-

Primary Outcome Measures

Name	Time	Method
Change in bacterial count in dental plaque	1 week, 2 weeks and 4 weeks	The samples will be collected from all children in the study and the level of S.mutans will be recorded.

Trial Locations

Locations (1)

Alexandria Faculty of Dentistry; 🇪🇬 Alexandria, Egypt