To evaluate the outcomes of placing steroid soaked absorbable material in the postoperative sinus cavity of patients undergoing surgery for chronic rhinosinusitis with nasal polyps.
Phase 3
- Conditions
- Health Condition 1: J330- Polyp of nasal cavity
- Registration Number
- CTRI/2023/06/054252
- Lead Sponsor
- Christian Medical College Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with Chronic rhinosinusitis with nasal polyposis refractory to maximal medical treatment and planned for endoscopic sinus surgery
Exclusion Criteria
a. Patients who used oral or nasal corticosteroids for 4 weeks before operation
b. Patients undergoing revision endoscopic sinus surgery
c. Presence of active infection within the sinus
d. Patients with Allergic fungal rhinosinusitis or invasive fungal sinusitis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Variables assessed <br/ ><br>Preoperative assessment: <br/ ><br>1) VAS score <br/ ><br>2) SNOT 22 scores <br/ ><br>3) Modified Lund Kennedy endoscopy scores <br/ ><br>4) Lund Mackay CT scores <br/ ><br>Postoperative assessment: <br/ ><br>1) VAS score <br/ ><br>2) SNOT 22 scores <br/ ><br>3) Modified Lund Kennedy endoscopy scoresTimepoint: Postoperative assessment: Day 7-10, 3 months
- Secondary Outcome Measures
Name Time Method Correlate the histopathological findings and total tissue eosinophil count with clinical and endoscopic outcomes.Timepoint: 3 months;Determine the incidence of eosinophilic and non-eosinophilic nasal polyps based on total tissue eosinophil count in the study population, <br/ ><br>. <br/ ><br>Timepoint: 1 month;To correlate the outcomes of eosinophilic and non-eosinophilic nasal polyps with the interventionTimepoint: 3 month