Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Tissue factor
研究概览
简要总结
Despite being generally benign tumors, meningiomas are associated with an increased risk for thrombembolic complications after surgical resection. The molecular mechanisms underlying this circumstance are still unknown.
In this prospective observational trial, the investigators aim to evaluate the changes in coagulation and platelet function caused by tumor resection.
Blood samples are obtained by patients undergoing meningioma resection before and immediately after resection to detect said changes.
As a control cohort, blood samples are obtained from patients undergoing resection for glioma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients undergoing resection for meningioma or
- •Patients undergoing resection for glioma or
- •Healthy controls
- •written consent for study participation
排除标准
- 未提供
结局指标
主要结局
Tissue factor
时间窗: duration of surfical tumor resection (a few hours)
Concentration of tissue factor at pre-surgery and immediately after tumor resection (during close-up).
次要结局
未报告次要终点