Disruptive mood and emotional conflict resolution in adolescent children of parents with recurrent depression or bipolar disorder and healthy controls

Completed

Conditions: Disruptive Mood Dysregulation Disorder
Mental and Behavioural Disorders

Registration Number: ISRCTN97724780

Lead Sponsor: Abant Izzet Baysal University Medical Faculty

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 96

Inclusion Criteria

For parents (in unipolar/bipolar groups):
1. Aged between 30- 65 years
2. Recurrent Major Depressive Disorder or Bipolar I/ II diagnosis (ascertained via SCID- I),
3. Followed at the outpatient department of Psychiatry of Abant Izzet Baysal University Medical Faculty,
4. Are in remission (CGI-S = 2, YMRS = 5, HAM-D-17 = 7)

For parents in control group:
1. Have brought their adolescent offspring for acute somatic symptoms to the pediatrics outpatient department of Abant Izzet Baysal University Medical Faculty within the study period
2. Are free of lifetime psychopathology (ascertained via SCID-I)

Exclusion Criteria

For parents (in unipolar/bipolar groups):
1. Active disorder (CGI-S > 2, YMRS > 5, HAM-D-17 > 7)
2. Epilepsy/chronic neurological disorders/mental retardation
3. Active psychotic symptoms
4. Illiteracy

For parents in control group:
1. Life time history of psychopathology
2. Epilepsy/chronic neurological disorders/mental retardation
3. Illiteracy

For adolescent offspring:
1. Epilepsy/chronic neurological disorders/mental retardation
2. Illiteracy

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reaction speed of adolescents in three groups (unipolar offspring, bipolar offspring, healthy controls) in emotional stroop trials (in milliseconds)

Secondary Outcome Measures

Name	Time	Method
1. Reaction speeds of adolescents in three groups (unipolar offspring, bipolar offspring, healthy controls) in Stroop Color Word Test - TBAG Form (in milliseconds)<br>2. Rates of psychopathologies (including DMDD) according to structured interviews (K-SADS-PL)