Oral memantine and pain after orthopedic surgery
Phase 2
- Conditions
- S80-S99Patients needing orthopedic surgery of the lower limbs below the knee.Injury, poisoning and certain other consequences of external causes
- Registration Number
- IRCT2015101824576N1
- Lead Sponsor
- Vice Chancellor for research of Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 110
Inclusion Criteria
Inclusion criteria including age range between 18 and 60 years, having indications for spinal anesthesia, having surgery of the lower limbs below the knee for bone plaque embedding. Exclusion criteria including any postoperative complication requires surgical intervention, lack of consent to participate in the study, having a history of substance abuse, history of chronic disease such as diabetes, high blood pressure and etc. taking medication, having a mental illness, having known hypersensitivity to the ketamine drug, having mental retardation and loss of consciousness, hemodynamic disorders, bleeding disorders and anemia
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: 30 and 60 minutes, 2, 12 and 24 hours after surgery. Method of measurement: VAS (Visual Analogue Scale) ruler.
- Secondary Outcome Measures
Name Time Method Consumption of Analgesic amount. Timepoint: 30 and 60 minutes, 2, 12 and 24 hours after surgery. Method of measurement: mg.