BCR-ABL Peptide Vaccination in Normal Subjects.An investigation in normal subjects with HLA-A3 and HLA-B8, as an extension of an identical study in patients with Chronic Myeloid Leukaemia. - BCR-ABL Peptide Vaccination in Normal Subjects.
- Conditions
- Healthy Subjects
- Registration Number
- EUCTR2005-001745-42-GB
- Lead Sponsor
- niversity of Liverpool and Royal Liverpool University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Aged 18 or over and previously a volunteer apheresis blood donorAble to give informed written consent.HLA-A3 and/or –B8 positiveNot currently donating to the National Blood ServiceNo serious concomitant illness (eg heart disease) that might preclude completion of the study.Serum creatinine, alanine transaminase and blood count within normal limits.Negative pregnancy test in women of childbearing age.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Pregnancy or lactatingReceiving steroids or other immunosuppressive agentsCurrently donating to National Blood Service
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method