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TB vaccination in diabetes populatio

Not Applicable
Conditions
Health Condition 1: E08-E13- Diabetes mellitus
Registration Number
CTRI/2022/07/044500
Lead Sponsor
Department of Biotechnology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Screening phase:

Willingness to undergo HIV testing.

Willingness to receive either intradermal BCG vaccine or placebo inoculation.

Willingness to provide repeat venous blood samples at D-3, D0 (the day of BCG or placebo inoculation), D7, D14, D28 and D56.

Willingness to have samples and data stored.

Able to provide informed consent.

Study phase:

Individuals are eligible for the study phase if they meet the requirements for one of the study groups, as follows:

Type 1 and 2 Diabetes will be included in the study. We cannot differentiate between Type1 and Type 2 diabetes based on HbA1c.

Group I: Latent tuberculosis infection (LTBI) negative long-term controllers no Diabetes mellitus (DM);

Group II: LTBI without Diabetes mellitus (DM);

Group III: LTBI Negative with Diabetes mellitus (DM); and

Group IV: LTBI with Diabetes mellitus (DM).

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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