Comparison Between Pericapsular Nerve Group (PENG) Block and Interscalene Brachial Plexus Block for Postoperative Analgesia Following Shoulder Arthroscopy

Not Applicable

Recruiting

• Conditions: Interscalene Brachial Plexus Block; Pericapsular Nerve Block; Shoulder Arthroscopy
• Interventions: Procedure: Pericapsular nerve group (PENG) block; Other: Control Group (Interscalene brachial plexus block)

• Registration Number: NCT06235879
• Lead Sponsor: Ain Shams University

Brief Summary

The study aimed to compare ultrasound guided pericapsular nerve group (PENG) block versus interscalene brachial plexus block for postoperative analgesia following shoulder arthroscopy.

Detailed Description

Shoulder arthroscopy can effectively treat a number of injuries and diseases of the shoulder on an ambulatory basis. Although shoulder arthroscopy is considered minimally invasive, it is related to severe postoperative pain. The use of arthroscopy is popular because it decreases pain, shortens hospital stay, and improves patient satisfaction. However, immediate postoperative pain remains to be a problem in more than 40% of patients.

Regional anesthesia, especially peripheral nerve blocks have various advantages like decreased need for postoperative analgesics, decreased incidence of nausea and vomiting, shortened recovery time and hospital stay, Early ambulation and discharge.

Interscalene brachial plexus (ISB) block is considered the gold standard technique for pain management in shoulder surgery as it provides the most reliable analgesia. However, it has the potential for many complications. The most common of these complications is phrenic nerve palsy, which is reversible but may result in significant respiratory distress especially in patients with compromised respiratory function. Other less common yet serious complications include Horner's syndrome, recurrent laryngeal nerve block that may result in hoarseness of voice, vascular puncture, brachial plexus neuropathy, and unintended injection of local anesthetic into the subarachnoid space, epidural space, or vertebral artery.

Pericapsular nerve group (PENG) block is a new block that provides a pericapsular distribution with local anesthetic infiltration around the glenohumeral joint and provides analgesia by reaching the sensory nerve branches of the glenohumeral joint.

Study Timeline

• Study First Submitted: 2024-01-20
• Study First Submitted QC: 2024-01-30
• Status Verified: 2024-02
• Study Start: 2024-02-01
• Study First Posted: 2024-02-01
• Last Update Submitted: 2024-02-01
• Last Update Posted: 2024-02-02
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age from 18 to 60 years old. - Both genders. - BMI ≤35 kg/m2. - American Society of Anesthesiologists Physical Status (ASA-PS) Class I and II. - Patient who will be scheduled for an elective unilateral arthroscopic shoulder surgery.

Exclusion Criteria

• Refusal of procedure or participation in the study
• Patient under age of 18 years old or above 60 years' old
• Physical status: ASA-PS III or above.
• Pregnancy or lactation.
• Infection at site of injection.
• Psychiatric illness.
• CNS Diseases like (epilepsy, stroke ...etc.) or neurological disease affecting patient's upper limb.
• Evidence of coagulopathy or anticoagulation.
• Patients with respiratory disease, renal or hepatic insufficiency.
• infection of the skin in the puncture area.
• Allergy against any of the drugs to be used.
• Obesity (BMI >35 kg/m2).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B (Pericapsular nerve group (PENG) block)	Pericapsular nerve group (PENG) block	Patients will receive ultrasound guided Pericapsular nerve group (PENG) block after induction of general anesthesia
Group A (Control Group	Control Group (Interscalene brachial plexus block)	Patients will receive ultrasound guided Interscalene brachial plexus (ISB) block after induction of general anesthesia.

Primary Outcome Measures

Name	Time	Method
First time for requiring analgesia	24 hours postoperatively	First time for requiring analgesia. It will be defined as the time from recovery until VAS score greater than 3.

Secondary Outcome Measures

Name	Time	Method
The degree of pain	24 hours postoperatively	The degree of pain will be measured using visual analogue scale (VAS)ranging from 0 to 10, where 0 no pain and 10 maximum pain. It will be evaluated on arrival to PACU (T0) then at 2, 4, 6, 12, and 24 h postoperatively.
Total amount of pethidine consumption in the first 24 hours	24 hours postoperatively	If the patient complained of pain, intravenous pethidine sulfate will be (50mg/dose) to be repeated on demand (VAS is \> 3) provided that the total 24-hour dosage not to exceed 50 mg every 6 hours.
Complications	24 hours postoperatively	Any complications during and after the performance of the block - for example, pneumothorax, Horner's syndrome, hoarseness of voice, difficulty in breathing, weakness, and paresthesia in the arm will be recorded.

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt