High Resolution Electroencephalography Exploration of Tactile Prediction Development
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Tactile prediction at 6
研究概览
简要总结
This project aims to measure repetition suppression and tactile prediction using high-resolution electroencephalography in preschoolers, in order to describe the responses as a function of age, gestational age of birth and the presence of a neurodevelopmental disorder. We will include 100 children aged 2 or 6 years: 25 2-year-olds born prematurely, 25 2-year-olds born at term, 25 6-year-olds with typical development and 25 6-year-olds with neurodevelopmental disorders. We will perform several behavioral evaluations to analyze the results in view of the quality of development.
详细描述
We will include 100 children aged 2 or 6 years: 25 2-year-olds born prematurely, 25 2-year-olds born at term, 25 6-year-olds with typical development and 25 6-year-olds with neurodevelopmental disorders. Children will be recruited from local schools and institutions. Birth will be considered premature if children were born before 36 weeks of gestational age. Children will be considered as having neurodevelopmental disorder if they receive medical and/or paramedical care at the time of measurement for neurodevelopmental disorder, including autism spectrum disorder, attention deficit with or without hyperactivity, tics, learning disorders, but all participants must be attending school at the time of measurement.
Children will come to the lab for a 2 hours session with their parents, during which they will undergo movement, attention and executive functions evaluations. Parents will fill out questionnaires evaluating their child's executive functioning and sensory profile in home/everyday settings. Children will then be equipped with 128-channels electroencephalography and proposed two tests : a modified attention network task and a tactile prediction task.
We will calculate correlations between evoked potential amplitudes during the tactile prediction trials and inhibitory conflict trials. Results will be analysed in the light of age, gestational age at birth, ecological and psychometric evaluations, and neurodevelopmental status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 2 Years 至 6 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 24 to 35 or 72 to 83 months
- •Born prematurely or term, with or without neurodevelopmental disorders (see arms)
- •Parental informed consent
- •Attending school
排除标准
- •Severe IQ deficit or language impairment
- •Psychotropic medication
研究组 & 干预措施
Typical 6
6-year-olds with typical developement
干预措施: Laby 5-12 (Behavioral)
Typical 6
6-year-olds with typical developement
干预措施: M-ABC 2 (Behavioral)
Preterm 2
2-year-olds born prematurely
干预措施: electroencephalography (Device)
Preterm 2
2-year-olds born prematurely
干预措施: Tactile stimulation (Device)
Term 2
2-year-olds born at term
干预措施: electroencephalography (Device)
Term 2
2-year-olds born at term
干预措施: Tactile stimulation (Device)
Typical 6
6-year-olds with typical developement
干预措施: electroencephalography (Device)
Typical 6
6-year-olds with typical developement
干预措施: Tactile stimulation (Device)
Typical 6
6-year-olds with typical developement
干预措施: Attention Network task (computerized) (Behavioral)
Typical 6
6-year-olds with typical developement
干预措施: Head-toes-knees-schoulders (Behavioral)
Typical 6
6-year-olds with typical developement
干预措施: Stroop animals (Behavioral)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: electroencephalography (Device)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: Tactile stimulation (Device)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: Attention Network task (computerized) (Behavioral)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: Head-toes-knees-schoulders (Behavioral)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: Laby 5-12 (Behavioral)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: M-ABC 2 (Behavioral)
NDD 6
6-year-olds with neurodevelopmental disorders
干预措施: Stroop animals (Behavioral)
结局指标
主要结局
Tactile prediction at 6
时间窗: 6 years
Difference of amplitude between baseline and omission segment
Tactile prediction at 2
时间窗: 2 years
Difference of amplitude between baseline and omission segment
Repetition suppression at 2
时间窗: 2 years
Difference of tactile evoked potential amplitude between end and beginning of stimulation sequence
Repetition suppression at 6
时间窗: 6 years
Difference of tactile evoked potential amplitude between end and beginning of stimulation sequence
次要结局
未报告次要终点
