Gene expression profiling of angiogenic factors in osteonecrosis of the jaw
- Conditions
- K10.28Osoteonecrosis of the jaw
- Registration Number
- DRKS00000728
- Lead Sponsor
- Mund- und Kiefer-GesichtschirurgieUniversitätsklinikum Münster
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
histologically diagnosed osteomyelitis radionecrosis or bisphosphonate associated osteonecrosis of the jaw, informed consent, 18 years or older, operability
Exclusion Criteria
younger than 18 years, no informed consent, no histologically confirmed diagnosis
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method what: performance of the genome arrays by microarray technique: Identification of significantly altered gene expression profile in the angiogenic pathway<br>when: october 2012<br>how: statistical analysis, clinical evaluation and correlation<br><br>
- Secondary Outcome Measures
Name Time Method what: collection of RNA samples<br>when: april 2012<br>how: storage of a RNA database