Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome

Completed

• Conditions: ST-Elevation Myocardial Infarction

• Registration Number: NCT00952224
• Lead Sponsor: University of Leipzig

Brief Summary

In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).

Detailed Description

Not available

Study Timeline

• Study Start: 2006-11
• Primary Completion: 2008-05
• Study Completion: 2009-03
• Status Verified: 2009-08
• Study First Submitted: 2009-08-03
• Study First Submitted QC: 2009-08-04
• Last Update Submitted: 2009-08-04
• Study First Posted: 2009-08-06
• Last Update Posted: 2009-08-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 267

Inclusion Criteria

• ST-elevation myocardial infarction < 12 hours
• primary percutaneous coronary intervention

Exclusion Criteria

• previous myocardial infarction
• prior fibrinolysis
• contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse cardiac events	6 months

Secondary Outcome Measures

Name	Time	Method
Mortality	6 months

Trial Locations

Locations (1)

University of Leipzig - Heart Center; 🇩🇪 Leipzig, Germany