Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
Completed
- Conditions
- ST-Elevation Myocardial Infarction
- Interventions
- Other: magnetic resonance imaging
- Registration Number
- NCT00952224
- Lead Sponsor
- University of Leipzig
- Brief Summary
In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 267
Inclusion Criteria
- ST-elevation myocardial infarction < 12 hours
- primary percutaneous coronary intervention
Exclusion Criteria
- previous myocardial infarction
- prior fibrinolysis
- contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Acute myocardial infarction patients magnetic resonance imaging Patients undergoing primary percutaneous coronary intervention in ST-elevation myocardial infarction plus magnetic resonance imaging
- Primary Outcome Measures
Name Time Method Major adverse cardiac events 6 months
- Secondary Outcome Measures
Name Time Method Mortality 6 months
Trial Locations
- Locations (1)
University of Leipzig - Heart Center
🇩🇪Leipzig, Germany